Anti-CERS2 Antibody

ceramide synthase 2
Recommended Applications
Product Description
Polyclonal Antibody against Human CERS2
Alternative Gene Names
FLJ10243, LASS2, SP260
Product Number
Unit Size
Lot dependent
>10 in Stock
Ready to Ship
Target Protein
ceramide synthase 2
Target Gene
Antigen Sequence
Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence
Verified Species Reactivity
Human, Mouse, Rat
Interspecies Information

Highest antigen sequence identity to the following orthologs:

Rat ENSRNOG00000021138 (95%)

Mouse ENSMUSG00000015714 (95%)

40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Material Safety Data Sheet
Purification Method
Affinity purified using the PrEST antigen as affinity ligand
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Unit Size
100 µl
Current Lot
Produced on demand. Contact for more information.
Product Data Sheet
Immunohistochemistry (IHC)

Recommended conditions:

Dilution: 1:500 - 1:1000

Retrieval method: HIER pH6

Western Blot (WB)

Recommended conditions:

Working concentration: 0.04-0.4 µg/ml

Immunofluorescence in Cell Lines (ICC-IF)

Recommended conditions:

Fixation/Permeabilization: PFA/Triton X-100

Working concentration: 0.25-2 µg/ml

Western Blot (WB)

Validated in Western blot using relevant lysates (see Western blot application images above)

Protein Name
ceramide synthase 2
Gene Name
Alternative Gene Names
FLJ10243, LASS2, SP260
UniProt ID
Gene (Ensembl)
Entrez Gene ID
Normally shipped at ambient temperature
Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Human Protein Atlas

This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.

All characterization data for ENSG00000143418 on the Human Protein Atlas

Pathak D, Mehendale N, Singh S, Mallik R, Kamat SS

Lipidomics Suggests a New Role for Ceramide Synthase in Phagocytosis

ACS Chem Biol , 2018 Jul 2; 13(8):2280-2287. Epub 2018 Jul 2

PubMed ID: 29963848 DOI: 10.1021/acschembio.8b00438

Spassieva SD, Ji X, Liu Y, Gable K, Bielawski J, Dunn TM, Bieberich E, Zhao L

Ectopic expression of ceramide synthase 2 in neurons suppresses neurodegeneration induced by ceramide synthase 1 deficiency

Proc Natl Acad Sci U S A , 2016 May 9; 113(21):5928-5933. Epub 2016 May 9

PubMed ID: 27162368 DOI: 10.1073/pnas.1522071113

Did we miss your publication?

Have you published using HPA027262? Please let us know and we will be happy to include your reference on this page.

Read more

Join the Explorer Program

Are you using our products in an application or species we have not yet tested? Why not participate in the Explorer Program, and we will show your contribution here. If you would like to share your results with us, the Explorer Program offers 50% of the product price as a refund, or 50% discount on your next vial purchase.

Read more

Corresponding Antigens


Our customer support and expert scientific support teams are here to help you succeed in your research.

Get in touch