Enhanced Validation

Anti-CDH6 Antibody

cadherin 6, type 2, K-cadherin (fetal kidney)
Recommended Applications
Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.
Product Description
Polyclonal Antibody against Human CDH6
Price
$445.00
Product Number
HPA007047
Unit Size
Concentration
Lot dependent
Availability
>10 in Stock
Ships
Ready to Ship
Target Protein
cadherin 6, type 2, K-cadherin (fetal kidney)
Target Gene
CDH6
Antigen Sequence
Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence
LDRETLLWHNITVIATEINNPKQSSRVPLYIKVLDVNDNAPEFAEFYETFVCEKAKADQLIQTLHAVDKDDPYSGHQFSFSLAPEAASGSNFTIQDNKDNTAGILTRKNGYNRHEMSTYLLP
Verified Species Reactivity
Human
Interspecies Information

Highest antigen sequence identity to the following orthologs:

Rat ENSRNOG00000013535 (100%)

Mouse ENSMUSG00000039385 (98%)

Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Buffer
40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Material Safety Data Sheet
Purification Method
Affinity purified using the PrEST antigen as affinity ligand
Notes
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Unit Size
100 µl
Current Lot
Produced on demand. Contact support@atlasantibodies.com for more information.
Concentration
Product Data Sheet
Immunohistochemistry (IHC)

Recommended conditions:

Dilution: 1:50 - 1:200

Retrieval method: HIER pH6

Protocols
Immunohistochemistry (IHC)

Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.

Protein Name
cadherin 6, type 2, K-cadherin (fetal kidney)
Gene Name
CDH6
UniProt ID
Gene (Ensembl)
Entrez Gene ID
Shipping
Normally shipped at ambient temperature
Storage
Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Human Protein Atlas

This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.

All characterization data for ENSG00000113361 on the Human Protein Atlas

M Gugnoni, V Sancisi, G Gandolfi, G Manzotti, M Ragazzi, D Giordano, I Tamagnini, M Tigano, A Frasoldati, S Piana, A Ciarrocchi

Cadherin-6 promotes EMT and cancer metastasis by restraining autophagy

Oncogene , July 04, 2016

PubMed ID: None DOI: 10.1038/onc.2016.237

Takasato M, Er PX, Becroft M, Vanslambrouck JM, Stanley EG, Elefanty AG, Little MH

Directing human embryonic stem cell differentiation towards a renal lineage generates a self-organizing kidney.

Nat Cell Biol , 2014 Jan; 16(1):118-26. Epub 2013 Dec 15

PubMed ID: 24335651 DOI: 10.1038/ncb2894

Sancisi V, Gandolfi G, Ragazzi M, Nicoli D, Tamagnini I, Piana S, Ciarrocchi A

Cadherin 6 Is a New RUNX2 Target in TGF-β Signalling Pathway

PLoS One , 2013; 8(9):e75489. Epub 2013 Sep 12

PubMed ID: 24069422 DOI: 10.1371/journal.pone.0075489

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Are you using our products in an application or species we have not yet tested? Why not participate in the Explorer Program, and we will show your contribution here. If you would like to share your results with us, the Explorer Program offers 50% of the product price as a refund, or 50% discount on your next vial purchase.

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Alternative Antibodies
Corresponding Antigens

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