Highest antigen sequence identity to the following orthologs:
Rat ENSRNOG00000017123 (74%)
Mouse ENSMUSG00000060802 (69%)
Dilution: 1:1000 - 1:2500
Retrieval method: HIER pH6
Working concentration: 0.04-0.4 µg/ml
Fixation/Permeabilization: PFA/Triton X-100
Working concentration: 0.25-2 µg/ml
Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.
Orthogonal validation of protein expression using WB by comparison to RNA-seq data of corresponding target in high and low expression cell lines.
This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.
Human leukocyte antigen class II expression is a good prognostic factor in adult T-cell leukemia/lymphoma
Haematologica , 2019 Aug; 104(8):1626-1632
Structure of the human MHC-I peptide-loading complex
Nature , 551, 525-528 (2017)
Immune profiling of NF1-associated tumors reveals histologic subtype distinctions and heterogeneity: implications for immunotherapy
Oncotarget , 2017 May 30; 8(47):82037-82048. Epub 2017 May 30
Antibody-based proteomics for discovery and exploration of proteins expressed in pancreatic islets.
Discov Med , 2010 Jun; 9(49):565-78
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