Highest antigen sequence identity to the following orthologs:
Rat ENSRNOG00000000991 (94%)
Mouse ENSMUSG00000029622 (94%)
Dilution: 1:200 - 1:500
Retrieval method: HIER pH6
Working concentration: 0.04-0.4 µg/ml
Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.
Orthogonal validation of protein expression using WB by comparison to RNA-seq data of corresponding target in high and low expression cell lines.
This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.
Loss of ARPC1B impairs cytotoxic T lymphocyte maintenance and cytolytic activity
J Clin Invest , 2019 Nov 11; 129(12):5600-5614. Epub 2019 Nov 11
Cortical branched actin determines cell cycle progression
Cell Res , 2019 Apr 10; 29(6):432-445. Epub 2019 Apr 10
Loss of the Arp2/3 complex component ARPC1B causes platelet abnormalities and predisposes to inflammatory disease
Nat Commun , 2017 Apr 3; 8:14816. Epub 2017 Apr 3
Phosphoproteomic comparison of Pik3ca and Pten signalling identifies the nucleotidase NT5C as a novel AKT substrate
Sci Rep , 2017 Jan 6; 7:39985. Epub 2017 Jan 6
Isoform diversity in the Arp2/3 complex determines actin filament dynamics
Nature Cell Biology , 18, 76-86 (2015)
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