Anti-AQP4 Antibody
Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.
Highest antigen sequence identity to the following orthologs:
Mouse ENSMUSG00000024411 (93%)
Rat ENSRNOG00000016043 (92%)
Recommended conditions:
Dilution: 1:2500 - 1:5000
Retrieval method: HIER pH6
Recommended conditions:
Working concentration: 0.4 µg/ml
Recommended conditions:
Fixation/Permeabilization: PFA/Triton X-100
Working concentration: 1-4 µg/ml
Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.
Validated in Western blot using relevant lysates (see Western blot application images above)
This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.
All characterization data for ENSG00000171885 on the Human Protein Atlas
Loss of the transcription factor RBPJ induces disease-promoting properties in brain pericytes
Nat Commun , 2019 Jun 27; 10:2817. Epub 2019 Jun 27
Therapeutic Target and Cell-signal Communication of Chlorpromazine and Promethazine in Attenuating Blood–Brain Barrier Disruption after Ischemic Stroke
Cell Transplant , 2018 Dec 20; 28(2):145-156. Epub 2018 Dec 20
Multiple origins and modularity in the spatiotemporal emergence of cerebellar astrocyte heterogeneity
PLoS Biol , 2018 Sep 27; 16(9):e2005513. Epub 2018 Sep 27
A recurrent point mutation in PRKCA is a hallmark of chordoid gliomas
Nat Commun , 2018 Jun 18; 9:2371. Epub 2018 Jun 18
A role for ErbB signaling in the induction of reactive astrogliosis
Cell Discov , 2017 Dec 5; 3:17044-. Epub 2017 Dec 5
Neurotoxic reactive astrocytes are induced by activated microglia
Nature , 2017 Jan 18; 541(7638):481-487. Epub 2017 Jan 18
Changes in Cannabinoid Receptors, Aquaporin 4 and Vimentin Expression after Traumatic Brain Injury in Adolescent Male Mice. Association with Edema and Neurological Deficit
PLoS One , 2015; 10(6):e0128782. Epub 2015 Jun 3
Human neural progenitor cells generated from induced pluripotent stem cells can survive, migrate, and integrate in the rodent spinal cord
J Comp Neurol , 2014 Aug 15; 522(12):2707-2728. Epub 2014 Apr 12
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