Polyclonal Anti-ANLN Antibody
Highest antigen sequence identity to the following orthologs:
Rat ENSRNOG00000014343 (76%)
Mouse ENSMUSG00000036777 (76%)
Dilution: 1:50 - 1:200
Retrieval method: HIER pH6
Working concentration: 0.04-0.4 µg/ml
Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.
Genetic validation in WB by siRNA knockdown.
This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.
Drak/STK17A drives neoplastic glial proliferation through modulation of MRLC signaling
Cancer Res , 2018 Dec 10; 79(6):1085-1097. Epub 2018 Dec 10
ANLN is a prognostic biomarker independent of Ki-67 and essential for cell cycle progression in primary breast cancer
BMC Cancer , 2016 Nov 18; 16:904. Epub 2016 Nov 18
Systematic antibody generation and validation via tissue microarray technology leading to identification of a novel protein prognostic panel in breast cancer.
BMC Cancer , 2013 Apr 2; 13:175. Epub 2013 Apr 2
Generation of monospecific antibodies based on affinity capture of polyclonal antibodies.
Protein Sci , 2011 Nov; 20(11):1824-35. Epub 2011 Oct 12
Join the Explorer Program
Are you using our products in an application or species we have not yet tested? Why not participate in the Explorer Program, and we will show your contribution here. If you would like to share your results with us, the Explorer Program offers a 25µl vial free of charge with your next order.