Polyclonal Anti-ADPRHL2 Antibody
Highest antigen sequence identity to the following orthologs:
Rat ENSRNOG00000010849 (91%)
Mouse ENSMUSG00000042558 (91%)
Dilution: 1:500 - 1:1000
Retrieval method: HIER pH6
Working concentration: 0.04-0.4 µg/ml
Fixation/Permeabilization: PFA/Triton X-100
Working concentration: 0.25-2 µg/ml
Genetic validation in WB by siRNA knockdown.
This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.
Pathogenic ARH3 mutations result in ADP-ribose chromatin scars during DNA strand break repair
Nat Commun , 2020 Jul 7; 11:3391. Epub 2020 Jul 7
Interplay of Histone Marks with Serine ADP-Ribosylation
Cell Rep , 2018 Sep 25; 24(13):3488-3502.e5. Epub 2018 Sep 25
Serine is the major residue for ADP-ribosylation upon DNA damage
eLife , 2018 Feb 26; 7:e34334. Epub 2018 Feb 26
Serine ADP-ribosylation reversal by the hydrolase ARH3
eLife , 2017 Jun 26; 6:e28533. Epub 2017 Jun 26
Join the Explorer Program
Are you using our products in an application or species we have not yet tested? Why not participate in the Explorer Program, and we will show your contribution here. If you would like to share your results with us, the Explorer Program offers a 25µl vial free of charge with your next order.