Highest antigen sequence identity to the following orthologs:
Mouse ENSMUSG00000010651 (88%)
Rat ENSRNOG00000032908 (87%)
Dilution: 1:50 - 1:200
Retrieval method: HIER pH6
Working concentration: 0.04-0.4 µg/ml
Fixation/Permeabilization: PFA/Triton X-100
Working concentration: 0.25-2 µg/ml
Validation of protein expression in IHC by comparing independent antibodies targeting different epitopes of the protein.
Validated against independent antibody Anti-ACAA1 HPA006764.
Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.
Validation of protein expression in WB by comparing independent antibodies targeting different epitopes of the protein.
This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.
HSD17B4, ACAA1, and PXMP4 in Peroxisome Pathway Are Down-Regulated and Have Clinical Significance in Non-small Cell Lung Cancer
Front Genet , 2020 Mar 20; 11:273. Epub 2020 Mar 20
Ceapins block the unfolded protein response sensor ATF6α by inducing a neomorphic inter-organelle tether
eLife , 2019 May 31; 8:e46595. Epub 2019 May 31
Allelic Expression Imbalance Promoting a Mutant PEX6 Allele Causes Zellweger Spectrum Disorder
Am J Hum Genet , 2017 Dec 7; 101(6):965-976. Epub 2017 Dec 7
Peroxisomes contribute to oxidative stress in neurons during doxorubicin-based chemotherapy
Mol Cell Neurosci , 2017 Nov 24; 86:65-71. Epub 2017 Nov 24
Peroxisomal abnormalities in the immortalized human hepatocyte (IHH) cell line
Histochem Cell Biol , 2016 Dec 24; 147(4):537-541. Epub 2016 Dec 24
Peripheral nervous system plasmalogens regulate Schwann cell differentiation and myelination
J Clin Invest , 2014 Jun; 124(6):2560-2570. Epub 2014 Apr 24
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