Monoclonal Anti-WWTR1 Antibody
Human Protein Atlas
Highest antigen sequence identity to the following orthologs:
Rat ENSRNOG00000016617 (96%)
Mouse ENSMUSG00000027803 (96%)
Dilution: 1:50 - 1:200
Retrieval method: HIER pH6
Working concentration: 1 µg/ml
Fixation/Permeabilization: PFA/Triton X-100
Working concentration: 2-10 µg/ml
Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.
Genetic validation in WB by siRNA knockdown.
The Hippo pathway effector TAZ induces intrahepatic cholangiocarcinoma in mice and is ubiquitously activated in the human disease
J Exp Clin Cancer Res , 2022 Jun 3; 41:192. Epub 2022 Jun 3
The Hippo Effector Transcriptional Coactivator with PDZ-Binding Motif Cooperates with Oncogenic β-Catenin to Induce Hepatoblastoma Development in Mice and Humans
Am J Pathol , 2020 Jul; 190(7):1397-1413
Hippo-YAP1 Is a Prognosis Marker and Potentially Targetable Pathway in Advanced Gallbladder Cancer
Cancers (Basel) , 2020 Mar 25; 12(4):778. Epub 2020 Mar 25
Join the Explorer Program
Are you using our products in an application or species we have not yet tested? Why not participate in the Explorer Program, and we will show your contribution here. If you would like to share your results with us, the Explorer Program offers a 25µl vial free of charge with your next order.