Triple A Polyclonals - Number 1 in IHC

We are proud to be the number one for IHC research antibodies. Find out why Triple A Polyclonals™ are the optimal antibodies to choose for your IHC experiments. 

What does it take to be the number one for IHC? It starts with offering you a catalog of over 17,000 highly validated IHC research antibodies. For each antibody, we provide you with 500 images in normal and cancerous tissues, with each annotated by a pathologist. Our deep knowledge within IHC is then supported by our own manufacturing and Quality Control, and guaranteed lot to lot reproducibility. Added to this is our team of highly qualified scientists here to support you. But we don’t stop there! At Atlas Antibodies we are proud to offer unique Enhance Validation of our antibodies.

Find the antibody you need in the world’s largest catalog of IHC validated research antibodies

You can choose between more than 17,000 IHC validated primary antibodies for your research. In our catalog you will find IHC antibodies against 75% of the human proteome. We're the original manufacturer of all our antibodies, Triple A Polyclonals and PrecisA Monoclonals. Triple A Polyclonals (Atlas Antibodies Advanced Polyclonals) are published on the Human Protein Atlas. They are validated in IHC on all major tissues and organs in the human body as well as the 20 most common cancer types. 

Discover antibodies optimal for your IHC assays

Triple A Polyclonals typically contain between 3-5 epitopes. This makes them optimal for IHC due to the higher assay sensitivity resulting from several epitopes compared to an antibody with only one epitope. Another advantage is the versatility this brings. Having several epitopes gives the antibody a higher chance to work in other species and applications. This is because it is less vulnerable to sample treatment, point mutations and also has better chance to detect different isoforms of the protein. If one epitope should be destroyed in sample preparation, be blocked or not be present in another species, there is a good chance that the Triple A Polyclonal will still bind to one of the other epitopes.

Get access to an unparalleled amount of IHC data and images

Triple A Polyclonals, developed to be used in the prestigious Human Protein Atlas project, are manufactured by and made available to fellow researchers by us at Atlas Antibodies. For every one of our Triple A Polyclonals, you have free access to over 500 IHC images from all major human organs and all major cancer types on the Human Protein Atlas. Every image is manually annotated by a skilled pathologist. Transparency is very important to us and we openly share data, providing all stained images as well as the antigen sequence used for our antibodies. 

Find IHC validated antibodies to unknown proteins

With our Triple A Polyclonals, we target the human proteome with IHC validated antibodies. This means that we can offer antibodies against uncommon or unknown proteins. These proteins may not have any previous literature or published data. For these proteins we offer the same amount of images and data as for all other proteins, showing the expression in all major tissues in the human body as well as the 20 most common cancer types.

Unique Enhanced Validation for IHC

The need for extensively validated antibodies expressed from the scientific community is perfectly in line with the mindset of Atlas Antibodies, where antibody validation and reproducibility always has been of the highest priority. Since IHC is a non-quantitative method our experienced personnel perform thorough manual analysis in an extensive number of human tissues to ensure specificity. We are adding enhanced validation data for our antibodies in an application-specific manner, using the approach recommended in Nature Methods by Uhlén et al.

You can trust lot-to-lot reproducibility in IHC

At Atlas Antibodies we know our antibodies. To ensure functionality and assay reproducibility in a real lab situation, every new production lot is tested in immunohistochemistry in parallel to existing lots in a large number of tissues.

The immune response may vary between animals, and therefore a polyclonal antibody purified from a new animal serum needs a stringent quality control procedure to secure retained specificity and functionality. At Atlas Antibodies, this is ensured by analyzing the new lot in parallel with its reference lot on consecutive tissue sections.

Get supported by our deep IHC knowledge and expertise

Do you have a question about IHC or about antibodies? We're committed to sharing our deep knowledge within IHC with you. Our Scientific Support team of highly qualified scientists is here to assist you, supported by our R&D and Quality Control teams.

Contact us at support@atlasantibodies.com, we look forward to hearing from you.