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Pan-Cancer Markers for Proteomic Phenotyping


Cancer involves complex molecular mechanisms beyond genetic mutations. While genomic and transcriptomic data are essential, protein-level expression provides direct insight into cellular function and tumor behavior.

This collection of Pan-Cancer markers includes over 300 primary antibodies, selected based on TCGA Pan-Cancer Atlas data and validated on human cancer tissues and cell lines. These markers support the identification of shared oncogenic pathways and are applicable across a broad range of tumor types.

All antibodies are IHC-validated and supported by additional data from the Human Protein Atlas database, offering robust tools for proteomic phenotyping and integrative cross-cancer research.

 

 

The Value of Atlas Antibodies Pan-Cancer Marker Collection

The Atlas Antibodies Pan-Cancer Marker Panel includes more than 300 antibodies for tissue and cell analysis. Each antibody is extensively validated across 20 human cancer types, ensuring robust performance and reliable results for comprehensive pan-cancer research.

Direct Protein Profiling

300+ antibodies: transcript levels don’t always reflect functional protein presence. Our antibodies allow direct detection of biologically relevant proteins.

High-Confidence

IHC-verified: all antibodies are validated through IHC on a wide panel of normal and cancer tissues to ensure specificity, consistency, and relevance.

Multi-Cancer Utility

20+ tumor types validated: targets are derived from cross-cancer analyses of human samples, making the collection ideal for broad, multiplexed cancer research.

 

Example of Pan-Cancer Markers

Marker Role in Cancer Cancer Involvement View Product
KI-67 (MKI67) Proliferation marker; enriched in dividing tumor cells. Breast, lung, colorectal, prostate, glioma, sarcoma AMAb90870
HER2 (ERBB2) Receptor tyrosine kinase; drives growth and survival. Breast, gastric, ovarian, lung AMAb90627
EZH2 Epigenetic regulator; promotes stemness and tumor progression. Prostate, breast, lymphomas, sarcomas, melanoma AMAb91749
CD44 Cell adhesion and migration; cancer stem cell-associated. Breast, colorectal, pancreatic, head & neck, prostate AMAb91845
ERCC1 DNA repair protein; linked to chemo resistance (platinum agents). Lung, ovarian, bladder, colorectal AMAb90871
ESR1 (ERα) Hormone receptor regulating proliferation and tumor growth. Breast, endometrial, ovarian AMAb90867

 

Explore Cancer Biology at the Protein Level:
Over 300 Pan-Cancer Markers Validated on Human Cancers

Explore our comprehensive collection of antibodies validated across multiple cancer types. Each antibody is extensively characterized with over 500 annotated IHC images including cancerous tissues, providing unmatched confidence for your research.

DOWNLOAD THE FULL MARKERS PANEL

 

Resources & Technical Documents

 

 

Scientific Support

Protocol optimization and technical guidance.


Our scientists at Atlas Antibodies and the Human Protein Atlas provide expert support and guidance to help you achieve reliable, reproducible results.
From experiment design to troubleshooting, we're here to assist every step of the way.
- Get in touch with our specialists - Request a quote - Stay tuned as new markers are added

 

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