Interview with a scientist: proteomics, biomarkers and ALS.
No effective therapies are currently available for Amyotrophic Lateral Sclerosis- ALS due to the lack of biomarkers for early diagnosis and monitoring disease progression. Meet here, Dr. Valentina Bonetto, and read about her research efforts based on proteomic assays to find validated biomarkers and innovative therapeutic strategies to treat ALS.
4 things I missed during the Society for Neuroscience virtual conference…or did I?
The Society for Neuroscience, SfN, holds an annual meeting that is attended by scientists and physicians from all around the world. This year, because of the ongoing pandemic, the meeting was run virtually. Did I enjoy it?
Two-years blog anniversary! A recap of our most popular posts
This month we celebrate the second birthday of our blog. If you have missed it read on. Here is a recap just for you.
How Enhanced Validation helps you publish your research
Do you know what to expect from a good antibody? How and when an antibody meets your expectations? Have you ever heard about enhanced validation? Read on to know more about it!
Interview with a scientist: traffic jams at the nuclear pores
Within our body, hundreds of molecules pass in and out across the cellular membranes, and, similarly to cars, they can get stuck in traffic jams. This nuclear-cytoplasmic trafficking might contribute to neurological disorders. Read more and learn about Dr. Rita Sattler's research.
Interview with a scientist: drug repurposing in oncology
Drug repurposing is the strategy of using existing drugs originally developed for a specific disease to treat other diseases. We have interviewed Dr. Joanna Zawacka-Pankau about her research in drug repurposing to treat cancer.
Now I see you: the imaging toolbox that improves the detection of primary ciliary dyskinesia
Ciliopathies are inherited human disorders that affect primary cilia genes. The authors of this study took part in our Explorer Program. Read on to discover what they found.
Liquid biopsy: what is written in the blood?
Liquid biopsy is a non-invasive sampling approach also used to predict the progression and growth dynamics of cancer and provide guidance for therapy monitoring. This blog covers various features and issues associated with liquid biopsy as exemplified by tumor markers.
How to determine the specificity of an antibody for Western Blot
Paramount for a successful Western blot, is the ability of the primary antibody to detect the protein of interest. But how to validate an antibody for Western blot?
How to achieve greater separation in Western blot when proteins have a similar size
Despite its overall simplicity, the Western Blot application is a powerful procedure for the immunodetection of proteins and an essential tool within biological research. Nevertheless, proteins of the same length or similar size, such as isoform of the same protein, are difficult to separate. With some adjustments you can however achieve great results. Here we share some tips.