GPCR Markers for Cancer Research
G protein-coupled receptors (GPCRs) constitute a diverse and crucial class of cell membrane proteins that mediate various physiological functions. In the context of cancer, GPCRs play a pivotal role by contributing to key processes such as cancer cell proliferation, angiogenesis (the formation of new blood vessels), invasion into surrounding tissues, and metastasis (the spread of cancer to distant organs).
The intricate signaling pathways activated by GPCRs in cancer cells make them attractive targets for therapeutic intervention.
The pharmacological inhibition of GPCRs and their downstream signaling targets presents a promising opportunity to develop novel, mechanism-based strategies for both the prevention and treatment of cancer. By disrupting the signaling cascades associated with GPCRs, researchers aim to impede the aberrant cellular processes that drive cancer progression.