Our polyclonal anti-RNF113A antibody in neural stem cells research

April 2022 (Center for Basic Research, Biomedical Research Foundation of the Academy of Athens, Greece)

RNF113A (Ring Finger Protein 113A) regulates survival and differentiation properties of neural stem cells.

Loss-of-function mutations in human RNF113A are associated with autism spectrum disorders and X-linked trichothiodystrophy (TTD) syndrome characterized by abnormal development of central nervous system and mental retardation.



This study by Tsampoula M. et al, (Stem Cells, 2022) identifies Rnf113a1 as a critical regulator of cell death and neurogenesis during mouse brain development and provide insights for its role in neurodevelopmental defects associated with autism and TTD.

Read more: https://lnkd.in/ds-8NtPC

The rabbit polyclonal anti-RNF113A antibody (HPA000160) from Atlas Antibodies was used in this study.