Anti-IGFBP6 polyclonal in various cancer types researches
May 2023 (Tumor Etiology and Screening Department of Cancer Institute and General Surgery, The First Hospital of China Medical University, No. 155 North Nanjing Street, Heping District, Shenyang, 110001, Liaoning, People’s Republic of China)
Insulin-like growth factor binding proteins (IGFBPs) are critical components of the insulin-like growth factor (IGF) system.
Members of the IGFBP family include 7 members with crucial functions as transcriptional regulators and inducers of apoptosis, thus playing essential roles in human cancers. However, we still lack a comprehensive understanding so far.
A new study published in BMC Cancer (2023) reports the expression characteristics and functional role of the IGFBP gene family in 20 types of human cancers.
Data were collected from multi-source databases, including the Human Protein Atlas database, for the immunohistochemical staining data of the IGFBP family in tumors.
Results show that members of the IGFBP gene family are differentially expressed in various cancer types affecting their prognosis.
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