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Anti-ATM Antibody
- ChIP-Certified
Polyclonal Antibody against HUMAN ATM
0.2 mg/ml
Immunofluorescent staining of human cell line EFO-21 using Anti-ATM antibody HPA067142, showing protein localization to nucleoplasm & vesicles (green). Microtubule and nuclear probes are visualized in red and blue, respectively (where available).
The Anti‑ATM antibody (HPA067142) targets ATM (ATM serine/threonine kinase), a key intracellular regulator classified by the Human Protein Atlas as a cancer‑related, disease‑related, and enzyme‑class protein. HPA reports low tissue specificity, with ATM expressed broadly across human tissues and clustered within “Retina & Lymphoid tissues – Signaling (mainly)”, reflecting its central role in DNA‑damage response and cellular stress signaling.
Significance in Research: HPA protein localization shows general nuclear expression, with ATM predominantly detected in the nucleoplasm, and additionally in vesicles and the Golgi apparatus, highlighting its involvement in genome protection and intracellular signaling networks. This antibody is ideal for researchers studying DNA repair pathways, cell‑cycle regulation, genomic stability, and ATM‑linked disease mechanisms, including cancer biology and immunological signaling.
Corresponding antigens
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Learn how we validate our antibodies, how we secure their reproducibility, and why we apply enhanced validation. Our antibodies are validated in IHC, ICC-IF, and WB.