All products are designed for the highest possible performance and are manufactured using a standardized process to ensure the most rigorous levels of quality.
Anti-CCR4 Antibody
Polyclonal Antibody against HUMAN CCR4
0.1 mg/ml
Immunohistochemical staining of human tonsil shows moderate to strong cytoplasmic positivity in a subset of lymphoid cells.
The Anti‑CCR4 antibody (HPA031613) is a highly specific reagent designed to detect CCR4 (C‑C chemokine receptor type 4), a key G protein–coupled receptor predominantly expressed on immune cell subsets such as Th2 cells and regulatory T cells (Tregs). CCR4 is crucial for chemokine‑guided cell trafficking and immune regulation, making this antibody a powerful tool for immunology, inflammation, and cancer research.
Significance in Research: CCR4 is essential for directing immune cell migration through chemokines such as CCL17 and CCL22, playing a central role in immune regulation and inflammatory responses. Abnormal CCR4 expression is closely linked to diseases including cutaneous T‑cell lymphoma (CTCL), adult T‑cell leukemia/lymphoma (ATLL), and chronic inflammatory conditions. In cancer, CCR4 drives an immunosuppressive tumor microenvironment by recruiting Tregs, and its high expression is associated with poor prognosis in several tumor types.
Corresponding antigens
With Atlas Antibodies you get
From our facilities in Stockholm, Sweden we develop, manufacture and distribute highly advanced reagents to the Life Sciences community worldwide.
Our products are available to customers worldwide. From most locations, you can order our products from Atlas Antibodies. Please see more information about how to order here.
Learn how we validate our antibodies, how we secure their reproducibility, and why we apply enhanced validation. Our antibodies are validated in IHC, ICC-IF, and WB.