👉 The 3 anti-EYA4 antibodies used in #immunohistochemistry on human tissues to evaluate the expression of EYA4 in normal breast tissue and breast carcinoma were:
EYA4 belong to a unique family of four dual-functioning protein phosphatases (PP), which have been linked to many vital cellular processes and organogenesis pathways.
EYA4 has been associated with several human cancers, with tumor-suppressing and tumor-promoting roles.
👉 By using 3 of our Triple A Polyclonals, this newly published study found that the over-expression of EYA4 in breast tissue leads to an aggressive and invasive breast cancer phenotype, while the inhibition of EYA4 reduced tumorigenic properties of breast cancer cells in vitro and in vivo.
Read full article here.