Targeted Proteomics

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QPrEST - High Accuracy Targeted Proteomics

Discover QPrEST™ standards - Stable Isotope-Labeled protein standards for absolute protein quantification using Mass Spectrometry. QPrEST standards offer high accuracy, are spiked in early in the workflow and are delivered ready-to-use. In our catalog, you can find QPrEST standards targeting the majority of human proteins.

QPrEST are on demand standards for protein quantification using mass spectrometry. QPrEST products are available for most human proteins.

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QPrEST+ are off-the-shelf standards for protein quantification. The products are accompanied with validation data, recommended quantotypic peptide and a product specific protocol.

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User Testimonials

“My group has been working with QPrESTs for many years and we have used them with great success for absolute quantification of proteins in a wide variety of sample types such as cell lines, tissues and plasma. I would highly recommend using QPrESTs since they are digested together with the sample which leads to very robust sample preparation and targeted proteomics assays with excellent repeatability”

Prof. Mathias Uhlén
Professor of Biotechnology, Royal Institute of Technology, Stockholm, Sweden

"We like to work with the QPrESTs in our targeted proteomic studies because they are easily available for a large number of proteins and they provide several peptides for quantification. A big advantage for us is also that peptides are surrounded by their natural amino acid sequence better reflecting the sample preparation process for absolute quantification."

Patrick Oeckl Ph.D.,
Department of Neurology, Ulm University Hospital, Germany

"We have been using QPrESTs in combination with MRM to quantify apolipoproteins in plasma samples from clinical trials and are very satisfied with the results. Addition of QPrEST standards enabled very low variation between replicate samples. Furthermore, QPrESTs bring the additional benefit that they are added together with the sample at the very first step of the sample preparation workflow and require to be trypsinated in order to release the peptide(s) used as the internal standard(s), hereby minimizing variation during sample digestion”

Tasso Miliotis Ph.D,
Associate Principal Scientist, AstraZeneca Gothenburg, Sweden

Featured Products

QPrEST+ APOL1 protein standard.

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QPrEST+ LPA protein standard.

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QPrEST+ LGR1 (A2GL) protein standard. 

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QPrEST+ APOA1 protein standard. 

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Unique QPrEST Technology

The QPrEST standards are designed to cover the most unique sequences within each human protein and to include large regions with several promising proteotypic peptides. QPrEST standards deliver high accuracy quantification for a wide range of sample types.

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Unique QPrEST Technology

QPrEST+ validated protein standards

The QPrEST+ standards are pre-produced and include defined quantotypic peptides validated for linear response and are suitable even for single-point calibration. QPrEST+ are accompanied with validation data, recommended quantotypic peptide and a product specific protocol.

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QPrEST+ validated protein standards
Featured White Paper

Read our white paper "QPrEST High Accuracy Targeted Proteomics" for a detailed description of our QPrEST technology and its benefits. The white paper covers:

  • Design and workflow
  • Quality control
  • Quantification
  • Accuracy and digestion
  • Application examples
  • Published research
Download white paper
NEW - Featured White Paper

Read our white paper "Validated Isotope-Labeled Protein Standard for Absolute Quantification Using Mass Spectrometry" for a detailed description of our QPrEST+ protein standards. The white paper covers: 

  • Validation according to the CPTAC assay criteria
  • Quantotypic peptides comparable to stable isotope-labeled full-length proteins
  • Linear responses for quantotypic peptides
  • Suitability for single-point calibration
Download white paper

Resources

FAQ

Have a question about QPrEST standards? Find your answer in our FAQ.

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Guarantee Program

All our products are covered by our Guarantee Program. 

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Protocols

Looking for a protocol? See our recommended protocols for QPrEST standards.

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Need Support?

Do you have a question about QPrEST standards or need help finding the right product? Get in touch with our support team. 

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