QPrEST - High Accuracy Targeted Proteomics
Discover QPrEST™ standards - Stable Isotope-Labeled protein standards for absolute protein quantification using Mass Spectrometry. QPrESTs offer high accuracy, spiked in early in the workflow and delivered ready-to-use. In our catalog, you can find QPrEST standards targeting the majority of the human proteins.
“My group has been working with QPrESTs for many years and we have used them with great success for absolute quantification of proteins in a wide variety of sample types such as cell lines, tissues and plasma. I would highly recommend using QPrESTs since they are digested together with the sample which leads to very robust sample preparation and targeted proteomics assays with excellent repeatability”
Mathias Uhlén, Professor of Biotechnology, Royal Institute of Technology, Stockholm, Sweden
"We like to work with the QPrESTs in our targeted proteomic studies because they are easily available for a large number of proteins and they provide several peptides for quantification. A big advantage for us is also that peptides are surrounded by their natural amino acid sequence better reflecting the sample preparation process for absolute quantification."
Patrick Oeckl Ph.D., Department of Neurology, Ulm University Hospital, Germany
"We have been using QPrESTs in combination with MRM to quantify apolipoproteins in plasma samples from clinical trials and are very satisfied with the results. Addition of QPrEST standards enabled very low variation between replicate samples. Furthermore, QPrESTs bring the additional benefit that they are added together with the sample at the very first step of the sample preparation workflow and require to be trypsinated in order to release the peptide(s) used as the internal standard(s), hereby minimizing variation during sample digestion”
Tasso Miliotis, Associate Principal Scientist, AstraZeneca Gothenburg
Unique QPrEST Technology
QPrESTs are Stable Isotope-Labeled protein standards for absolute protein quantification using Mass Spectrometry. The QPrESTs are designed to cover the most unique sequence within each human protein and to include regions with several promising proteotypic peptides. The QPrESTs are added early on in the workflow and deliver high accuracy quantification for a wide range of sample types.
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