Highest antigen sequence identity to the following orthologs:
Mouse ENSMUSG00000001507 (84%)
Rat ENSRNOG00000004276 (82%)
Dilution: 1:50 - 1:200
Retrieval method: HIER pH6
Working concentration: 0.04-0.4 µg/ml
Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.
Orthogonal validation of protein expression using WB by comparison to RNA-seq data of corresponding target in high and low expression cell lines.
Recombinant expression validation in WB using target protein overexpression.
This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.
High integrin α3 expression is associated with poor prognosis in patients with non-small cell lung cancer
Transl Lung Cancer Res , 2020 Aug; 9(4):1361-1378
Regulation of ITGA3 by the anti‐tumor miR‐199 family inhibits cancer cell migration and invasion in head and neck cancer
Cancer Sci , 2017 Jul 4; 108(8):1681-1692. Epub 2017 Jul 4
Regulation of ITGA3 by the dual-stranded microRNA-199 family as a potential prognostic marker in bladder cancer
Br J Cancer , 2017 Mar 21; 116(8):1077-1087. Epub 2017 Mar 21
Deep sequencing-based microRNA expression signatures in head and neck squamous cell carcinoma: dual strands of pre-miR-150 as antitumor miRNAs
Oncotarget , 2017 Mar 17; 8(18):30288-30304. Epub 2017 Mar 17
α3β1 Integrin suppresses prostate cancer metastasis via regulation of the Hippo pathway
Cancer Res , 2016 Sep 28; 76(22):6577-6587. Epub 2016 Sep 28
Tumor‐suppressive microRNA‐223 inhibits cancer cell migration and invasion by targeting ITGA3/ITGB1 signaling in prostate cancer
Cancer Sci , 2016/01/01; 107(1):84-94. Epub 2015 Dec 5
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