Highest antigen sequence identity to the following orthologs:
Rat ENSRNOG00000022171 (87%)
Mouse ENSMUSG00000029480 (87%)
Dilution: 1:50 - 1:200
Retrieval method: HIER pH6
Fixation/Permeabilization: PFA/Triton X-100
Working concentration: 0.25-2 µg/ml
Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.
This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.
Pathogenic variants in the DEAH-box RNA helicase DHX37 are a frequent cause of 46,XY gonadal dysgenesis and 46,XY testicular regression syndrome
Genet Med , 2019 Jul 24; 22(1):150-159. Epub 2019 Jul 24
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