Highest antigen sequence identity to the following orthologs:
Mouse ENSMUSG00000019987 (82%)
Rat ENSRNOG00000013304 (81%)
Dilution: 1:2500 - 1:5000
Retrieval method: HIER pH6
Working concentration: 0.04-0.4 µg/ml
Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.
Validation of protein expression in WB by comparing independent antibodies targeting different epitopes of the protein.
This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.
LmjF.22.0810 from Leishmania major Modulates the Th2-Type Immune Response and Is Involved in Leishmaniasis Outcome
Biomedicines , 2020 Oct 26; 8(11):452. Epub 2020 Oct 26
Alpha-Fetoprotein-Producing Early Gastric Cancer with Intramucosal Hepatoid and Fetal Enteric Differentiation
Case Rep Gastroenterol , 2020 Aug 26; 14(2):426-435. Epub 2020 Aug 26
M2-Polarized Macrophages Determine Human Cutaneous Lesions in Lacaziosis
Mycopathologia , . Epub 2020 May 6
Evaluation of Glycosylated PTGS2 in Colorectal Cancer for NSAIDS-Based Adjuvant Therapy
Cells , 2020 Mar 11; 9(3):683. Epub 2020 Mar 11
High-density neutrophils in MGUS and multiple myeloma are dysfunctional and immune-suppressive due to increased STAT3 downstream signaling
Sci Rep , 2020 Feb 6; 10:1983. Epub 2020 Feb 6
Plasticity of High-Density Neutrophils in Multiple Myeloma is Associated with Increased Autophagy Via STAT3
Int J Mol Sci , 2019 Jul 19; 20(14):3548. Epub 2019 Jul 19
The prognostic value of the myeloid-mediated immunosuppression marker Arginase-1 in classic Hodgkin lymphoma
Oncotarget , 2016 Sep 14; 7(41):67333-67346. Epub 2016 Sep 14
Arginase regulates red blood cell nitric oxide synthase and export of cardioprotective nitric oxide bioactivity
Proc Natl Acad Sci U S A , 2013 Sep 10; 110(37):15049-15054. Epub 2013 Aug 26
Arginase inhibition improves endothelial function in patients with coronary artery disease and type 2 diabetes mellitus.
Circulation , 2012 Dec 18; 126(25):2943-50. Epub 2012 Nov 26
Local Arginase Inhibition during Early Reperfusion Mediates Cardioprotection via Increased Nitric Oxide Production
PLoS One , 2012; 7(7):e42038. Epub 2012 Jul 31
Arginase inhibition restores in vivo coronary microvascular function in type 2 diabetic rats.
Am J Physiol Heart Circ Physiol , 2011 Apr; 300(4):H1174-81. Epub 2011 Feb 4
Arginase-1: A New Immunohistochemical Marker of Hepatocytes and Hepatocellular Neoplasms
Am J Surg Pathol , 2010 Aug; 34(8):1147-1154
A Quantitative Proteomic Approach for Identification of Potential Biomarkers in Hepatocellular Carcinoma
J Proteome Res , 2008 Oct; 7(10):4289-4298. Epub 2008 Aug 21
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