Our anti-S100b monoclonal in wound healing research
August 2022 (Shanghai Jiao Tong University School of Medicine, China)
Schwann cells facilitate wound healing by releasing TGF-β3.
Wound healing is among the most complicated physiological processes and requires the synchronization of various cell types with distinct roles to re-establish the condition of the original skin.
Loss of Schwann cells, a crucial population of peripheral nervous system cells in the skin, may contribute to chronic wounds. However, the role of Schwann cells in wound healing is poorly understood.
A newly published study by Min-Yi Ou et al. (Theranostics. 2022; 12(12): 5470–5487) advances the understanding of the roles of neural-derived cells in skin regeneration and suggests a potential therapeutic strategy for wound healing disorders.
Featured in this study is our mouse anti-S100b PrecisA monoclonal antibody AMAB91038, used in immunofluorescence to characterize Schwann cells in normal and diabetic wounds.